Celiac Disease Screening Test

Simple at-home screening for celiac disease

The most comprehensive at-home celiac test available. An easy way to self-screen for celiac disease, which is one of the most under-diagnosed diseases in the world — affecting almost 3 million Americans. It utilizes the gold standard tTG-IgA biomarker to understand how your body reacts to gluten.

Biomarkers tested:
Collection method:
Finger prick sample
with code HOLIDAY21
FSA/HSA cards accepted
Free shipping
Results in 10 business days
Results in 7 business days
Out of stock

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We will notify you when this test becomes available.

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We will notify you when this test becomes available.

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We will notify you when this test becomes available.

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This test measures 4 key biomarkers related to celiac disease

A celiac-specific biomarker is a measurable indicator of your body's response or condition to gluten. We utilize the screening gold standard — the highly sensitive Tissue Transglutaminase (tTG) Antibody, or tTG-IgA biomarker. For an even more comprehensive view of your results, we also screen for three additional biomarkers: tTG-lgG, DGP-IgG and DGP-IgA, designed to identify immunoglobulin deficiencies. Together, these unique biomarkers provide a complete analysis that goes beyond baseline testing to help you better understand your condition⁴⁻⁵.

View List of Allergens

Common symptoms of celiac disease to watch for:

There are over 300 symptoms associated with celiac disease, making it easy to miss or confuse for another condition. Digestive problems are the most commonly experienced symptoms among people with celiac disease, but it can also result in other effects — or none at all, as sometimes seen in family members of celiac patients³. The following symptoms are strong indicators that you should get tested:

Nausea or vomiting

Stomach cramps

Weight loss

Digestion issues

Regular bloating

*If you are experiencing heart attack symptoms, please see a doctor immediately.

3.6 Million

Over 1.1% of Americans are currently affected by celiac disease¹


Of those who are affected are currently undiagnosed¹⁻²

What is celiac disease?

Celiac disease is one of the most under diagnosed diseases in the world. It is a condition where the absorptive surface of the small intestine is damaged by a substance called gluten.

Gluten can be found in wheat, rye, barley, and other cross bred grains. This damage leads results in an inability of the body to absorb nutrients which are necessary for a healthy body.

Who is the most at risk?

As a genetic disease, celiac disease can be inherited; those with family members who have celiac disease are at higher risk. Someone suffering from autoimmune disease, such as thyroid disease or type 1 diabetes, is also at higher risk for celiac disease — as are patients with preexisting genetic disorders, such as Down Syndrome or Turner Syndrome.

What’s the benefit of early testing?

It takes the average American over 3 years from recognizing symptoms to be diagnosed with celiac disease. The best way to fight this disease is through early detection, allowing a patient to adjust their lifestyle habits. The earlier the diagnosis, the earlier a patient can improve their quality of life by reducing unnecessary pain and suffering.

What you get with imaware

Uncover life-impacting health data and get a complete picture of your health.

CLIA Certified Labs

Our laboratories are based in the United States, and CLIA  & CAP certified.

Physician Reviewed

Results are physician reviewed once the sample has been processed.

Secure Data

We use industry-grade encryption to ensure your data is always protected.

How it works

Our 3-step testing process provides peace of mind, no appointment necessary. Just order your home health kit online, collect & mail back your sample, then review your physician verified results online in less than a week.

A hand holding a collection device
1. Prepare & Collect

Prepare for collection, activate your kit, and collect your sample at home.

A hand putting the product box back in an envelope
2. Secure & Ship

Secure and send in your sample on the same day using the prepaid label.

A hand holding an iPhone with a sample report
3. Review & Action

View confidential and accurate results online in your secure portal within 7 business days.

View confidential and accurate results online in your secure portal within 10 business days.

You will receive an easy to read and actionable digital lab report that helps you understand:

Whether you may have the condition
How likely you are to have the condition
How to engage your healthcare professional
How to track your progress over time

Celiac Disease Screening Test FAQ's

Who can order an imaware™ test?

This test is only for adults aged 18 and older.

What if I have IgA deficiency?

An estimated 2% of people with celiac disease also have selective immunoglobulin A (IgA) deficiency. If someone has IgA deficiency and celiac disease, the IgA deficiency can cause a false negative on a celiac disease antibody test. However, those with IgA deficiency should be tested for celiac disease because they are 10 to 20 times more likely to develop an autoimmune response to gluten than the general population.

To navigate a false positive, those with IgA deficiency should be tested for IgG-tTG antibodies instead of IgA-tTG. That's why we include the IgG-tTG antibodies testing in our celiac screening test. Please note, like any celiac disease blood test, you will have to go back to eating gluten regularly for at least 6 weeks prior to testing - of course, please see a doctor if you are suffering a severe allergic reaction when consuming gluten. Read more about IgA deficiency.

Does the celiac disease screening test diagnose you with celiac disease?

 No, at this time you can only be diagnosed with an upper endoscopy biopsy, which is prescribed and carried out by a medical professional. A positive celiac disease screening result with imaware™ provides accurate likelihood based on a lab analysis of 4 key biomarkers. If likelihood is high, your results report can be used to engage with a gastroenterologist to continue along on your path to a diagnosis.

Do I really have to go back to eating gluten if I've already been gluten-free?

Unfortunately, yes. Your blood test (and subsequent small intestinal biopsy) will not be accurate if you are not eating enough gluten. You'll need to go back to a gluten-containing diet for at least 6 weeks for any blood test to be valid. If you have an allergy to wheat or consuming any amount of gluten makes you very ill, please consult with a physician first.

What is the difference between the celiac disease screening and the celiac disease monitoring tests?

The celiac disease screening test is for those that are still eating gluten, designed to provide a scale of likelihood that someone has the disease. The celiac disease monitoring test, on the other hand, is for those already diagnosed with celiac disease who want to make sure their biomarker levels are declining into a normal range with a strict gluten-free diet. The monitoring test measures the effectiveness of a gluten-free diet based on your biomarkers trending down over a period of time¹².

What will my results tell me?

Your imaware™ celiac screening test results will tell you how likely you are to have celiac disease. A blood test is only the first step to diagnosis, but it will provide a clear indicator of likelihood. Results that indicate a high likelihood of having celiac disease can be used to engage with a gastroenterologist for an endoscopy and biopsy to confirm active celiac disease.

Who should take this test?

This test is ideal for anyone experiencing:

  • Regular digestive distress
  • Unexplained weight loss
  • Fatigue
  • Itchy skin rash 
  • Unexplained anemia 

Anyone with a family history, specifically a first-degree relative with celiac disease, should be screened for celiac disease regularly since it increases your risk of having the disease.

Can my doctor use imaware™ results?

Yes. All of our tests are performed by CLIA-certified labs, the gold standard in lab testing quality regulation. Within your results report you will also find detailed information intended for your healthcare professional. They can use this information to interpret your test results clearly. To see an example of this, you can request a sample report at the top of this page.

How should I prepare for this test?

If you are not currently eating gluten regularly (at least a few crackers worth of gluten-containing food a day), you must add gluten back into your diet for 6-8 weeks before taking the celiac disease screening test. Do not take this test if you are currently following a gluten-free diet, as your results will not be accurate. If you have an allergy to wheat or experience a severe reaction when consuming any volume of gluten, please consult with a physician first.

Are imaware™ results as accurate as traditional lab test?

Yes. Not only are your results as accurate as traditional lab tests, but we’re actually the first at-home small volume blood testing company to have our data and methods peer-reviewed by the scientific and medical community — which helps validate our claims and our results reports. Learn more about the exact science behind imaware tests.

How do I receive my test results?

You’ll receive an email from us within 7 business days of your sample return. The email will contain a link to view and download your test results on our secure digital health platform once they’ve been analyzed by our labs and reviewed by a doctor.

Are imaware™ test results reviewed by a doctor?

Yes, all our test results are reviewed by a physician during the lab analysis process to ensure the third party validation of your results.

My state requires physician orders for tests like imaware™. Do you provide this for me?

Yes, we provide physician orders for every test in every state (even those that do not require them). You don’t need to get a prescription or pay extra for this service as it’s included in the purchase price of each test.


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